AZD0156 '-Di-O-methylellagic acid-4'-O-β-D-glucopyranoside Smiles: CC(C)(O)/C(/C)=C/C(=O)O[C@@H]1[C@H]2C3(OC[C@]42[C@H]([C@@H](O)[C@@H]3O)[C@@]2(C)CC(=O)C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C(C)[C@@H]2C[C@H]4OC1=O)C(=O)OC

Smiles: CC(C)(O)/C(/C)=C/C(=O)O[C@@H]1[C@H]2C3(OC[C@]42[C@H]([C@@H](O)[C@@H]3O)[C@@]2(C)CC(=O)C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C(C)[C@@H]2C[C@H]4OC1=O)C(=O)OC

24-48 h) increase of LDH leakage in both concentration- and time-dependent manner in HepG2 cells

clearance (4

InChiKey: WXJFKKQWPMNTIM-VWLOTQADSA-N

Polyethylene glycol nonyl phenyl ether) are nonionic surfactants used as detergents

AZD0156 '-Di-O-methylellagic acid-4'-O-β-D-glucopyranoside Smiles: CC(C)(O)/C(/C)=C/C(=O)O[C@@H]1[C@H]2C3(OC[C@]42[C@H]([C@@H](O)[C@@H]3O)[C@@]2(C)CC(=O)C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C(C)[C@@H]2C[C@H]4OC1=O)C(=O)OCAZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0. 58 nM. AZD0156 inhibits the ATM mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis. Product information CAS Number: 1821428 35 6 Molecular Weight: 461. 56 Formula: C26H31N5O3 Chemical Name: 8 {6 [3 (dimethylamino)propoxy]pyridin 3 yl} 3 methyl 1 (oxan 4 yl) 1H,2H,3H imidazo[4,5 c]quinolin 2 one